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Last updated about 21 hours ago
A resurrected ancestor of Cas12a expands target access and substrate recognition for nucleic acid editing and detection
about 21 hours ago
Nature Biotechnology, Published online: 31 October 2024; doi:10.1038/s41587-024-02461-3ReChb is a Cas12a nuclease...
Comprehensive genome analysis and variant detection at scale using DRAGEN
7 days ago
Nature Biotechnology, Published online: 25 October 2024; doi:10.1038/s41587-024-02382-1DRAGEN rapidly identifies diverse types...
A structurally informed human protein–protein interactome reveals proteome-wide perturbations caused by disease mutations
8 days ago
Nature Biotechnology, Published online: 24 October 2024; doi:10.1038/s41587-024-02428-4Protein–protein interactomes incorporating structural data...
Gold-siRNA supraclusters enhance the anti-tumor immune response of stereotactic ablative radiotherapy at primary and metastatic tumors
8 days ago
Nature Biotechnology, Published online: 24 October 2024; doi:10.1038/s41587-024-02448-0Gold-siRNA clusters boost the immune...
Pest control gets the CRISPR treatment
9 days ago
Nature Biotechnology, Published online: 23 October 2024; doi:10.1038/s41587-024-02449-zPrecision genetic methods are enabling...
Droplet Hi-C enables scalable, single-cell profiling of chromatin architecture in heterogeneous tissues
14 days ago
Nature Biotechnology, Published online: 18 October 2024; doi:10.1038/s41587-024-02447-1Chromatin organization is measured in...
Global profiling of protein complex dynamics with an experimental library of protein interaction markers
16 days ago
Nature Biotechnology, Published online: 16 October 2024; doi:10.1038/s41587-024-02432-8FLiP–MS uses a library of...
Lung and liver editing by lipid nanoparticle delivery of a stable CRISPR–Cas9 ribonucleoprotein
16 days ago
Nature Biotechnology, Published online: 16 October 2024; doi:10.1038/s41587-024-02437-3An engineered clustered regularly interspaced...
Bispecific upstages Keytruda
18 days ago
Nature Biotechnology, Published online: 14 October 2024; doi:10.1038/s41587-024-02451-5Bispecific upstages Keytruda
Pan-KRAS destruction with a single PROTAC
18 days ago
Nature Biotechnology, Published online: 14 October 2024; doi:10.1038/s41587-024-02445-3Pan-KRAS destruction with a single...
From Bench to Podcast: Chloe Fishman
18 days ago
Nature Biotechnology, Published online: 14 October 2024; doi:10.1038/s41587-024-02433-7From Bench to Podcast: Chloe...
A strategy to load, rethread and read protein sequences through a nanopore
18 days ago
Nature Biotechnology, Published online: 14 October 2024; doi:10.1038/s41587-024-02443-5A strategy to load, rethread...