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Last updated about 18 hours ago
Method of moments framework for differential expression analysis of single-cell RNA sequencing data
about 18 hours ago
Memento implements a statistical model and a fast resampling procedure to estimate...
Microbial transformation of dietary xenobiotics shapes gut microbiome composition
about 18 hours ago
Individuals can exhibit significant interpersonal variation in diet-microbiome interaction. This report uncovers...
Targeting Ras-, Rho-, and Rab-family GTPases via a conserved cryptic pocket
about 18 hours ago
Morstein et al. demonstrate the feasibility of inhibiting GTPases beyond K-Ras, including...
Emergence of community behaviors in the gut microbiota upon drug treatment
about 18 hours ago
A comparison of the effects of pharmaceuticals on different gut bacterial species...
Retraction notice to: hnRNP K: An HDM2 Target and Transcriptional Coactivator of p53 in Response to DNA Damage
about 18 hours ago
(Cell 123, 1065–1078; December 16, 2005)
Metformin decelerates aging clock in male monkeys
about 18 hours ago
Prolonged metformin treatment diminishes the multidimensional biological age and alleviates neuronal aging...
Light-induced remodeling of phytochrome B enables signal transduction by phytochrome-interacting factor
about 18 hours ago
Cryo-EM structures of Arabidopsis photoactivated phyB and its constitutively active phyBY276H mutant...
A two-front nutrient supply environment fuels small intestinal physiology through differential regulation of nutrient absorption and host defense
about 18 hours ago
Spatiotemporal mapping of the environment of the mouse small intestine enables the...
In vivo DNA replication dynamics unveil aging-dependent replication stress
about 18 hours ago
In vivo DNA replication dynamics in regenerating mouse livers unveil aging-dependent decline...
CSF proteomics identifies early changes in autosomal dominant Alzheimer’s disease
about 18 hours ago
Examination of CSF proteins in mutation carriers and non-carriers for autosomal dominant...
A pontine-medullary loop crucial for REM sleep and its deficit in Parkinson’s disease
about 18 hours ago
A neuronal circuit originating in the brainstem pons and medulla strongly induces...
Fine-grained descending control of steering in walking Drosophila
about 18 hours ago
The brain's role in generating purposeful locomotion depends on a set of...