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Last updated about 24 hours ago

Statistical inference with a manifold-constrained RNA velocity model uncovers cell cycle speed modulations

about 24 hours ago

Nature Methods, Published online: 31 October 2024; doi:10.1038/s41592-024-02471-8VeloCycle is a manifold-constrained generative...

Uncovering cell cycle speed modulations with statistical inference

about 24 hours ago

Nature Methods, Published online: 31 October 2024; doi:10.1038/s41592-024-02484-3A Bayesian inference framework improves...

Proteome-scale recombinant standards and a robust high-speed search engine to advance cross-linking MS-based interactomics

about 24 hours ago

Nature Methods, Published online: 31 October 2024; doi:10.1038/s41592-024-02478-1This Article reports cross-linking mass...

Quality control for single-cell analysis of high-plex tissue profiles using CyLinter

1 day ago

Nature Methods, Published online: 30 October 2024; doi:10.1038/s41592-024-02328-0Microscopy artifacts and tissue imperfections...

Inferring allele-specific copy number aberrations and tumor phylogeography from spatially resolved transcriptomics

1 day ago

Nature Methods, Published online: 30 October 2024; doi:10.1038/s41592-024-02438-9This work presents CalicoST for...

CryoSTAR: leveraging structural priors and constraints for cryo-EM heterogeneous reconstruction

3 days ago

Nature Methods, Published online: 29 October 2024; doi:10.1038/s41592-024-02486-1CryoSTAR is a deep neural...

SCUBA-D: a freshly trained diffusion model generates high-quality protein structures

4 days ago

Nature Methods, Published online: 28 October 2024; doi:10.1038/s41592-024-02465-6The accuracy of SCUBA-D, a...

Multiomic characterization of RNA microenvironments by oligonucleotide-mediated proximity-interactome mapping

4 days ago

Nature Methods, Published online: 28 October 2024; doi:10.1038/s41592-024-02457-6Oligonucleotide-mediated proximity-interactome MAPping (O-MAP) enables...

Cryo-electron microscopy in color

8 days ago

Nature Methods, Published online: 24 October 2024; doi:10.1038/s41592-024-02427-yCryo-electron microscopy with energy resolution...

Elemental mapping in single-particle reconstructions by reconstructed electron energy-loss analysis

8 days ago

Nature Methods, Published online: 24 October 2024; doi:10.1038/s41592-024-02482-5An approach combining electron energy-loss...

Differentiating visceral sensory ganglion organoids from induced pluripotent stem cells

10 days ago

Nature Methods, Published online: 22 October 2024; doi:10.1038/s41592-024-02455-8A protocol for differentiating visceral...

Influence of different sample preparation approaches on proteoform identification by top-down proteomics

10 days ago

Nature Methods, Published online: 22 October 2024; doi:10.1038/s41592-024-02481-6A systematic analysis of the...