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Last updated about 20 hours ago
Perturb-tracing enables high-content screening of multi-scale 3D genome regulators
about 20 hours ago
Nature Methods, Published online: 10 April 2025; doi:10.1038/s41592-025-02652-zThis work presents Perturb-tracing, integrating...
PTM-Mamba: a PTM-aware protein language model with bidirectional gated Mamba blocks
about 20 hours ago
Nature Methods, Published online: 10 April 2025; doi:10.1038/s41592-025-02656-9PTM-Mamba is a post-translational modification-aware...
Computer vision for primate behavior analysis in the wild
about 20 hours ago
Nature Methods, Published online: 10 April 2025; doi:10.1038/s41592-025-02653-yIn this Perspective, Vogg et...
Pooled CRISPR screening with optical sequencing reveals regulators of 3D chromatin organization
about 20 hours ago
Nature Methods, Published online: 10 April 2025; doi:10.1038/s41592-025-02633-2The Perturb-Tracing approach represents a...
CAVE: Connectome Annotation Versioning Engine
1 day ago
Nature Methods, Published online: 09 April 2025; doi:10.1038/s41592-024-02426-zThe Connectome Annotation Versioning Engine...
CRISPR–Csm guided RNA imaging
1 day ago
Nature Methods, Published online: 09 April 2025; doi:10.1038/s41592-025-02672-9CRISPR RNA-targeting tools enable the...
Efficient and robust search of microbial genomes via phylogenetic compression
1 day ago
Nature Methods, Published online: 09 April 2025; doi:10.1038/s41592-025-02625-2Phylogenetic compression achieves performant and...
The big picture in science
1 day ago
Nature Methods, Published online: 09 April 2025; doi:10.1038/s41592-025-02679-2Basic science and methods development...
Understanding protein subcellular compartmentalization signals
1 day ago
Nature Methods, Published online: 09 April 2025; doi:10.1038/s41592-025-02674-7Understanding protein subcellular compartmentalization signals
Learning the immunological repertoire
1 day ago
Nature Methods, Published online: 09 April 2025; doi:10.1038/s41592-025-02673-8Learning the immunological repertoire
Scaling a foundational protein language model to 100 billion parameters
8 days ago
Nature Methods, Published online: 03 April 2025; doi:10.1038/s41592-025-02637-yxTrimoPGLM, a protein language model...
xTrimoPGLM: unified 100-billion-parameter pretrained transformer for deciphering the language of proteins
8 days ago
Nature Methods, Published online: 03 April 2025; doi:10.1038/s41592-025-02636-zxTrimo protein general language model...